Indication:
Levagen 10, containing Lenvatinib in 10mg capsules, is prescribed for the treatment of various cancers, including thyroid cancer, advanced kidney cancer, and advanced liver cancer.

Pharmacology:
Lenvatinib, classified as a tyrosine kinase inhibitor, operates by obstructing numerous receptors crucial for tumor growth and angiogenesis, such as vascular endothelial growth factor receptors (VEGFR), fibroblast growth factor receptors (FGFR), among others. By inhibiting these pathways, Lenvatinib suppresses both tumor growth and angiogenesis.

Dosage and Administration:
The recommended dosage of Levagen 10 is generally taken orally once daily, with or without food. The precise dosage may vary based on the patient’s weight, tolerance to treatment, and the type of cancer being addressed. Adjustments or interruptions in dosage might be necessary depending on individual patient factors and the occurrence of adverse reactions.

Interaction:
Levagen 10 has the potential to interact with various medications, including other tyrosine kinase inhibitors, anticoagulants, and drugs affecting liver function. Patients must inform their healthcare provider about all medications, supplements, and herbal products they are using to prevent potential interactions.

Side Effects:
Typical adverse effects of Levagen 10 may comprise hypertension, diarrhea, fatigue, reduced appetite, and nausea. However, more severe side effects such as hepatotoxicity, proteinuria, thromboembolism, and cardiac events may also manifest. Patients should promptly seek medical attention if they experience severe or persistent side effects.

Precautions and Warnings:
Patients undergoing treatment with Levagen 10 should undergo regular monitoring of blood pressure, liver function, and thyroid function. Use of Lenvatinib during pregnancy may result in fetal harm, necessitating contraception for both genders during treatment and for a specified period afterward. Breastfeeding is not recommended while taking Levagen 10.

Overdose Effects:
In instances of Levagen 10 overdose, patients may experience intensified adverse effects such as hypertension, proteinuria, and gastrointestinal symptoms. Management typically involves supportive care and monitoring for complications. Immediate medical attention is crucial if overdose is suspected.