E-Medicare Pharma
Online Medicine Pharmacy
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Indication: Capmatinib, under the International Nonproprietary Name (INN) Capmatinib, is prescribed for treating metastatic non-small cell lung cancer (NSCLC) in adults with specific mutations in the MET gene.
Pharmacology: Capmatinib acts as a potent and selective inhibitor of the MET receptor tyrosine kinase. By binding to the MET receptor, it blocks its activation and downstream signaling pathways, effectively inhibiting tumor cell growth, survival, and spread.
Dosage and Administration: Capmatinib is typically administered orally at a dose of 400 mg twice daily, with or without food. Treatment should continue until either disease progression or intolerable adverse effects emerge.
Interactions: Potential interactions may occur with medications that affect CYP3A4 and CYP2C8 enzymes. It is advisable to avoid combining Capmatinib with potent CYP3A4 inhibitors or inducers. Caution is warranted when co-administering drugs that prolong the QT interval or substrates of P-glycoprotein.
Side Effects: Common side effects of Capmatinib comprise peripheral edema, nausea, vomiting, fatigue, reduced appetite, diarrhea, and elevated liver enzymes. Serious adverse reactions may include interstitial lung disease/pneumonitis, liver toxicity, and QT interval prolongation.
Precautions and Warnings:
Overdose Effect: In cases of overdose, supportive care is essential. No specific antidote for Capmatinib overdose exists, necessitating close monitoring for adverse reactions and prompt initiation of appropriate symptomatic treatment as required.
Product Name | Capmaxen |
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Generic Name | Capmatinib INN |
Formulation | Tablet |
Available Pack Size | 56 Tablets |
Available Strength | 200 mg |
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Online Medicine Pharmacy
+8801929123476 emedicarepharma@gmail.com
65, mymansingh High-way, Dhaka-1230, Bangladesh